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Bioluminescence imaging of G protein-coupled receptor activation in living mice
G protein-coupled receptors (GPCRs), a superfamily of cell-surface receptors involved in virtually all physiological processes, are the major target class for approved drugs. Imaging GPCR activation in real time in living animals would provide a powerful way to study their role in biology and diseas...
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Publicado en: | Nat Commun |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660082/ https://ncbi.nlm.nih.gov/pubmed/29079828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01340-7 |
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