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Bioluminescence imaging of G protein-coupled receptor activation in living mice

G protein-coupled receptors (GPCRs), a superfamily of cell-surface receptors involved in virtually all physiological processes, are the major target class for approved drugs. Imaging GPCR activation in real time in living animals would provide a powerful way to study their role in biology and diseas...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kono, Mari, Conlon, Elizabeth G., Lux, Samantha Y., Yanagida, Keisuke, Hla, Timothy, Proia, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660082/
https://ncbi.nlm.nih.gov/pubmed/29079828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01340-7
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