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Bioluminescence imaging of G protein-coupled receptor activation in living mice
G protein-coupled receptors (GPCRs), a superfamily of cell-surface receptors involved in virtually all physiological processes, are the major target class for approved drugs. Imaging GPCR activation in real time in living animals would provide a powerful way to study their role in biology and diseas...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660082/ https://ncbi.nlm.nih.gov/pubmed/29079828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01340-7 |
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