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A synthetic luciferin improves bioluminescence imaging in live mice

Firefly luciferase is the most widely used optical reporter for noninvasive bioluminescence imaging (BLI) in rodents. BLI relies on the ability of the injected luciferase substrate D-luciferin to access luciferase-expressing cells and tissues within the animal. Here we show that injection of mice wi...

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Bibliografske podrobnosti
Main Authors: Evans, Melanie S., Chaurette, Joanna P., Adams, Spencer T., Reddy, Gadarla R., Paley, Miranda A., Aronin, Neil, Prescher, Jennifer A., Miller, Stephen C.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026177/
https://ncbi.nlm.nih.gov/pubmed/24509630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2839
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