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Expedient synthesis of electronically modified luciferins for bioluminescence imaging
Bioluminescence imaging with luciferase enzymes requires access to light-emitting, small molecule luciferins. Here, we describe a rapid method to synthesize d-luciferin, the substrate for firefly luciferase (Fluc), along with a novel set of electronically modified analogs. Our procedure utilizes a r...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613990/ https://ncbi.nlm.nih.gov/pubmed/22519459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja301493d |
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