Brominated luciferins are versatile bioluminescent probes

We report a set of brominated luciferins for bioluminescence imaging. These regioisomeric scaffolds were accessed using a common synthetic route. All analogs produced light with firefly luciferase, although varying levels of emission were observed. Differences in photon output were analyzed via comp...

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Veröffentlicht in:Chembiochem
Hauptverfasser: Steinhardt, Rachel C., Rathbun, Colin M., Krull, Brandon T., Yu, Jason, Yang, Yuhang, Nguyen, Brian D., Kwon, Jake, McCutcheon, David C., Jones, Krysten A., Furche, Filipp, Prescher, Jennifer A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304417/
https://ncbi.nlm.nih.gov/pubmed/27930848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600564
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