Mitochondrial permeability transition pore in Alzheimer’s disease: cyclophilin D and amyloid beta

di Du, Heng, Yan, Shirley ShiDu
Pubblicazione 2009

Mitochondrial medicine for neurodegenerative diseases

di Du, Heng, Yan, Shirley ShiDu
Pubblicazione 2010

Unlocking the Door to Neuronal Woes in Alzheimer’s Disease: Aβ and Mitochondrial Permeability Transition Pore

di Du, Heng, Yan, Shirley ShiDu
Pubblicazione 2010

Synaptic Mitochondrial Pathology in Alzheimer's Disease

di Du, Heng, Guo, Lan, Yan, Shirley ShiDu
Pubblicazione 2012

Mitochondrial permeability transition pore: a potential drug target for neurodegeneration

di Kalani, Komal, Yan, Shi Fang, Yan, Shirley ShiDu
Pubblicato in Drug Discov Today (2018)

From a Cell’s Viewpoint: Targeting Mitochondria in Alzheimer’s disease

di Carlson, Emily Ann, Rao, Valasani Koteswara, Yan, Shirley ShiDu
Pubblicato in Drug Discov Today Ther Strateg (2013)

Mitochondrial Perturbation in Alzheimer’s Disease and Diabetes

di Akhter, Firoz, Chen, Doris, Yan, Shi Fang, Yan, Shirley ShiDu
Pubblicato in Prog Mol Biol Transl Sci (2017)

Hypoxia Inducible Factor-1 as a Target for Neurodegenerative Diseases

di Zhang, Ziyan, Yan, Jingqi, Chang, Yanzhong, Yan, Shirley ShiDu, Shi, Honglian
Pubblicazione 2011

Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model

di Fang, Fang, Chen, Xiaochun, Huang, Tianwen, Luddy, John S, Yan, Shirley ShiDu
Pubblicazione 2011

Structure-Based Design and Synthesis of Benzothiazole Phosphonate Analogues with Inhibitors of Human ABAD-Aβ for Treatment of Alzheimer’s disease

di Valasani, Koteswara Rao, Hu, Gang, Chaney, Michael O., Yan, Shirley ShiDu
Pubblicazione 2012

RAGE Inhibition in Microglia Prevents Ischemia-Dependent Synaptic Dysfunction in an Amyloid-Enriched Environment

di Origlia, Nicola, Criscuolo, Chiara, Arancio, Ottavio, Yan, Shirley ShiDu, Domenici, Luciano
Pubblicazione 2014

Identification of human presequence protease (hPreP) agonists for the treatment of Alzheimer’s disease

di Vangavaragu, Jhansi Rani, Valasani, Koteswara Rao, Gan, Xueqi, Yan, Shirley ShiDu
Pubblicato in Eur J Med Chem (2014)

Blockade of Drp1 rescues oxidative stress-induced osteoblast dysfunction

di Gan, Xueqi, Huang, Shengbin, Yu, Qing, Yu, Haiyang, Yan, Shirley ShiDu
Pubblicato in Biochem Biophys Res Commun (2015)

Mfn2 is Required for Mitochondrial Development and Synapse Formation in Human Induced Pluripotent Stem Cells/hiPSC Derived Cortical Neurons

di Fang, Du, Yan, Shijun, Yu, Qing, Chen, Doris, Yan, Shirley ShiDu
Pubblicato in Sci Rep (2016)

Development and Dynamic Regulation of Mitochondrial Network in Human Midbrain Dopaminergic Neurons Differentiated from iPSCs

di Fang, Du, Qing, Yu, Yan, Shijun, Chen, Doris, Yan, Shirley ShiDu
Pubblicato in Stem Cell Reports (2016)

RAGE is a key cellular target for Aβ-induced perturbation in Alzheimer's disease

di Yan, Shirley ShiDu, Chen, Doris, Yan, Shiqian, Guo, Lan, Chen, John Xi
Pubblicazione 2012

Structure Based Design, Synthesis, Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Novel Cyclophilin D Inhibitors

di Valasani, Koteswara Rao, Vangavaragu, Jhansi Rani, Day, Victor W., Yan, Shirley ShiDu
Pubblicazione 2014

Overexpression of 17β-hydroxysteroid dehydrogenase type 10 increases pheochromocytoma cell growth and resistance to cell death

di Carlson, Emily A, Marquez, Rebecca T, Du, Fang, Wang, Yongfu, Xu, Liang, Yan, Shirley ShiDu
Pubblicato in BMC Cancer (2015)

Determination of Small Molecule ABAD Inhibitors Crossing Blood Brain Barrier and Pharmacokinetics

di Vangavaragu, Jhansi Rani, Valasani, Koteswara Rao, Fang, Du, Williams, Todd D., Yan, Shirley ShiDu
Pubblicato in J Alzheimers Dis (2014)

Mitochondrial Dysfunction Triggers Synaptic Deficits via Activation of p38 MAP Kinase Signaling in Differentiated Alzheimer’s Disease Trans-Mitochondrial Cybrid Cells

di Yu, Qing, Du, Fang, Douglas, Justin T., Yu, Haiyang, Yan, Shirley ShiDu, Yan, Shi Fang
Pubblicato in J Alzheimers Dis (2017)