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Blockade of Drp1 rescues oxidative stress-induced osteoblast dysfunction

Osteoblast dysfunction, induced by oxidative stress, plays a critical role in the pathophysiology of osteoporosis. However, the underlying mechanisms remain unclarified. Imbalance of mitochondrial dynamics has been closely linked to oxidative stress. Here, we reveal an unexplored role of dynamic rel...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Gan, Xueqi, Huang, Shengbin, Yu, Qing, Yu, Haiyang, Yan, Shirley ShiDu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834976/
https://ncbi.nlm.nih.gov/pubmed/26577411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.11.022
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