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Determination of Small Molecule ABAD Inhibitors Crossing Blood Brain Barrier and Pharmacokinetics
A major obstacle to the development of effective treatment of Alzheimer’s disease (AD) is successfully delivery of drugs to the brain. We have previously identified a series of benzothiazole phosphonate compounds that block the interaction of amyloid beta peptide (Aβ) with amyloid-beta binding alcoh...
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| Publicat a: | J Alzheimers Dis |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4422494/ https://ncbi.nlm.nih.gov/pubmed/24858403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-140252 |
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