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Determination of Small Molecule ABAD Inhibitors Crossing Blood Brain Barrier and Pharmacokinetics

A major obstacle to the development of effective treatment of Alzheimer’s disease (AD) is successfully delivery of drugs to the brain. We have previously identified a series of benzothiazole phosphonate compounds that block the interaction of amyloid beta peptide (Aβ) with amyloid-beta binding alcoh...

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Dades bibliogràfiques
Publicat a:J Alzheimers Dis
Autors principals: Vangavaragu, Jhansi Rani, Valasani, Koteswara Rao, Fang, Du, Williams, Todd D., Yan, Shirley ShiDu
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422494/
https://ncbi.nlm.nih.gov/pubmed/24858403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-140252
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