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Structure Based Design, Synthesis, Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Novel Cyclophilin D Inhibitors

[Image: see text] Cyclophilin D (CypD) is a peptidyl prolyl isomerase F that resides in the mitochondrial matrix and associates with the inner mitochondrial membrane during the mitochondrial membrane permeability transition. CypD plays a central role in opening the mitochondrial membrane permeabilit...

詳細記述

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書誌詳細
主要な著者: Valasani, Koteswara Rao, Vangavaragu, Jhansi Rani, Day, Victor W., Yan, Shirley ShiDu
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985759/
https://ncbi.nlm.nih.gov/pubmed/24555519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci5000196
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