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Structure Based Design, Synthesis, Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Novel Cyclophilin D Inhibitors
[Image: see text] Cyclophilin D (CypD) is a peptidyl prolyl isomerase F that resides in the mitochondrial matrix and associates with the inner mitochondrial membrane during the mitochondrial membrane permeability transition. CypD plays a central role in opening the mitochondrial membrane permeabilit...
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| Hoofdauteurs: | , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical Society
2014
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985759/ https://ncbi.nlm.nih.gov/pubmed/24555519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci5000196 |
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