Mitochondrial permeability transition pore in Alzheimer’s disease: cyclophilin D and amyloid beta

Por Du, Heng, Yan, Shirley ShiDu
Publicado em 2009

Mitochondrial medicine for neurodegenerative diseases

Por Du, Heng, Yan, Shirley ShiDu
Publicado em 2010

Unlocking the Door to Neuronal Woes in Alzheimer’s Disease: Aβ and Mitochondrial Permeability Transition Pore

Por Du, Heng, Yan, Shirley ShiDu
Publicado em 2010

Synaptic Mitochondrial Pathology in Alzheimer's Disease

Por Du, Heng, Guo, Lan, Yan, Shirley ShiDu
Publicado em 2012

Mitochondrial permeability transition pore: a potential drug target for neurodegeneration

Por Kalani, Komal, Yan, Shi Fang, Yan, Shirley ShiDu
Publicado no Drug Discov Today (2018)

From a Cell’s Viewpoint: Targeting Mitochondria in Alzheimer’s disease

Por Carlson, Emily Ann, Rao, Valasani Koteswara, Yan, Shirley ShiDu
Publicado no Drug Discov Today Ther Strateg (2013)

Mitochondrial Perturbation in Alzheimer’s Disease and Diabetes

Por Akhter, Firoz, Chen, Doris, Yan, Shi Fang, Yan, Shirley ShiDu
Publicado no Prog Mol Biol Transl Sci (2017)

Hypoxia Inducible Factor-1 as a Target for Neurodegenerative Diseases

Por Zhang, Ziyan, Yan, Jingqi, Chang, Yanzhong, Yan, Shirley ShiDu, Shi, Honglian
Publicado em 2011

Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model

Por Fang, Fang, Chen, Xiaochun, Huang, Tianwen, Luddy, John S, Yan, Shirley ShiDu
Publicado em 2011

Structure-Based Design and Synthesis of Benzothiazole Phosphonate Analogues with Inhibitors of Human ABAD-Aβ for Treatment of Alzheimer’s disease

Por Valasani, Koteswara Rao, Hu, Gang, Chaney, Michael O., Yan, Shirley ShiDu
Publicado em 2012

RAGE Inhibition in Microglia Prevents Ischemia-Dependent Synaptic Dysfunction in an Amyloid-Enriched Environment

Por Origlia, Nicola, Criscuolo, Chiara, Arancio, Ottavio, Yan, Shirley ShiDu, Domenici, Luciano
Publicado em 2014

Identification of human presequence protease (hPreP) agonists for the treatment of Alzheimer’s disease

Por Vangavaragu, Jhansi Rani, Valasani, Koteswara Rao, Gan, Xueqi, Yan, Shirley ShiDu
Publicado no Eur J Med Chem (2014)

Blockade of Drp1 rescues oxidative stress-induced osteoblast dysfunction

Por Gan, Xueqi, Huang, Shengbin, Yu, Qing, Yu, Haiyang, Yan, Shirley ShiDu
Publicado no Biochem Biophys Res Commun (2015)

Mfn2 is Required for Mitochondrial Development and Synapse Formation in Human Induced Pluripotent Stem Cells/hiPSC Derived Cortical Neurons

Por Fang, Du, Yan, Shijun, Yu, Qing, Chen, Doris, Yan, Shirley ShiDu
Publicado no Sci Rep (2016)

Development and Dynamic Regulation of Mitochondrial Network in Human Midbrain Dopaminergic Neurons Differentiated from iPSCs

Por Fang, Du, Qing, Yu, Yan, Shijun, Chen, Doris, Yan, Shirley ShiDu
Publicado no Stem Cell Reports (2016)

RAGE is a key cellular target for Aβ-induced perturbation in Alzheimer's disease

Por Yan, Shirley ShiDu, Chen, Doris, Yan, Shiqian, Guo, Lan, Chen, John Xi
Publicado em 2012

Structure Based Design, Synthesis, Pharmacophore Modeling, Virtual Screening, and Molecular Docking Studies for Identification of Novel Cyclophilin D Inhibitors

Por Valasani, Koteswara Rao, Vangavaragu, Jhansi Rani, Day, Victor W., Yan, Shirley ShiDu
Publicado em 2014

Overexpression of 17β-hydroxysteroid dehydrogenase type 10 increases pheochromocytoma cell growth and resistance to cell death

Por Carlson, Emily A, Marquez, Rebecca T, Du, Fang, Wang, Yongfu, Xu, Liang, Yan, Shirley ShiDu
Publicado no BMC Cancer (2015)

Determination of Small Molecule ABAD Inhibitors Crossing Blood Brain Barrier and Pharmacokinetics

Por Vangavaragu, Jhansi Rani, Valasani, Koteswara Rao, Fang, Du, Williams, Todd D., Yan, Shirley ShiDu
Publicado no J Alzheimers Dis (2014)

Mitochondrial Dysfunction Triggers Synaptic Deficits via Activation of p38 MAP Kinase Signaling in Differentiated Alzheimer’s Disease Trans-Mitochondrial Cybrid Cells

Por Yu, Qing, Du, Fang, Douglas, Justin T., Yu, Haiyang, Yan, Shirley ShiDu, Yan, Shi Fang
Publicado no J Alzheimers Dis (2017)