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Mitochondrial permeability transition pore: a potential drug target for neurodegeneration

The mitochondrial permeability transition pore (mPTP) has been considered a key contributor to cell death, inducing the process in several major neurodegenerative diseases. To date, the molecular nature of the mPTP remains confounding but its significance is universally acknowledged. Several targets...

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Detalhes bibliográficos
Publicado no:Drug Discov Today
Main Authors: Kalani, Komal, Yan, Shi Fang, Yan, Shirley ShiDu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449145/
https://ncbi.nlm.nih.gov/pubmed/30081095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2018.08.001
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