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Mitochondrial permeability transition pore: a potential drug target for neurodegeneration

The mitochondrial permeability transition pore (mPTP) has been considered a key contributor to cell death, inducing the process in several major neurodegenerative diseases. To date, the molecular nature of the mPTP remains confounding but its significance is universally acknowledged. Several targets...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Discov Today
Prif Awduron: Kalani, Komal, Yan, Shi Fang, Yan, Shirley ShiDu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449145/
https://ncbi.nlm.nih.gov/pubmed/30081095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2018.08.001
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