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Mitochondrial permeability transition pore: a potential drug target for neurodegeneration

The mitochondrial permeability transition pore (mPTP) has been considered a key contributor to cell death, inducing the process in several major neurodegenerative diseases. To date, the molecular nature of the mPTP remains confounding but its significance is universally acknowledged. Several targets...

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Enregistré dans:
Détails bibliographiques
Publié dans:Drug Discov Today
Auteurs principaux: Kalani, Komal, Yan, Shi Fang, Yan, Shirley ShiDu
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449145/
https://ncbi.nlm.nih.gov/pubmed/30081095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2018.08.001
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