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Mitochondrial permeability transition pore: a potential drug target for neurodegeneration

The mitochondrial permeability transition pore (mPTP) has been considered a key contributor to cell death, inducing the process in several major neurodegenerative diseases. To date, the molecular nature of the mPTP remains confounding but its significance is universally acknowledged. Several targets...

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Podrobná bibliografie
Vydáno v:Drug Discov Today
Hlavní autoři: Kalani, Komal, Yan, Shi Fang, Yan, Shirley ShiDu
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449145/
https://ncbi.nlm.nih.gov/pubmed/30081095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2018.08.001
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