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Mitochondrial permeability transition pore in Alzheimer’s disease: cyclophilin D and amyloid beta

Amyloid beta (Aβ) plays a critical role in the pathophysiology of Alzheimer’s disease. Increasing evidence indicates mitochondria as an important target of Aβ toxicity; however, the effects of Aβ toxicity on mitochondria have not yet been fully elucidated. Recent biochemical studies in vivo and in v...

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Detalhes bibliográficos
Main Authors: Du, Heng, Yan, Shirley ShiDu
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280723/
https://ncbi.nlm.nih.gov/pubmed/19616093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2009.07.005
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