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Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

The mitochondrial permeability transition pore (mPTP) opening plays a critical role in mediating cell death during ischemia/reperfusion (I/R) injury. Our previous studies have shown that cysteine 203 of cyclophilin D (CypD), a critical mPTP mediator, undergoes protein S-nitrosylation (SNO). To inves...

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Bibliografski detalji
Glavni autori: Nguyen, Tiffany T., Stevens, Mark V., Kohr, Mark, Steenbergen, Charles, Sack, Michael N., Murphy, Elizabeth
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220546/
https://ncbi.nlm.nih.gov/pubmed/21930693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243469
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