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Mitochondrial permeability transition pore: a potential drug target for neurodegeneration

The mitochondrial permeability transition pore (mPTP) has been considered a key contributor to cell death, inducing the process in several major neurodegenerative diseases. To date, the molecular nature of the mPTP remains confounding but its significance is universally acknowledged. Several targets...

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Publicat a:Drug Discov Today
Autors principals: Kalani, Komal, Yan, Shi Fang, Yan, Shirley ShiDu
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449145/
https://ncbi.nlm.nih.gov/pubmed/30081095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2018.08.001
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