Wolbachia from the planthopper Laodelphax striatellus establishes a robust, persistent, streptomycin-resistant infection in clonal mosquito cells

Por Fallon, A. M., Baldridge, G. D., Higgins, L. A., Witthuhn, B. A.
Publicado em 2012

Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop.

Por Feng, J, Witthuhn, B A, Matsuda, T, Kohlhuber, F, Kerr, I M, Ihle, J N
Publicado em 1997

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

Por Silvennoinen, O, Witthuhn, B A, Quelle, F W, Cleveland, J L, Yi, T, Ihle, J N
Publicado em 1993

Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.

Por Narazaki, M, Witthuhn, B A, Yoshida, K, Silvennoinen, O, Yasukawa, K, Ihle, J N, Kishimoto, T, Taga, T
Publicado em 1994

Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes.

Por Beadling, C, Guschin, D, Witthuhn, B A, Ziemiecki, A, Ihle, J N, Kerr, I M, Cantrell, D A
Publicado em 1994

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

Por Guschin, D, Rogers, N, Briscoe, J, Witthuhn, B, Watling, D, Horn, F, Pellegrini, S, Yasukawa, K, Heinrich, P, Stark, G R
Publicado em 1995

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region.

Por Quelle, F W, Sato, N, Witthuhn, B A, Inhorn, R C, Eder, M, Miyajima, A, Griffin, J D, Ihle, J N
Publicado em 1994

Interleukin 4 signals through two related pathways.

Por Pernis, A, Witthuhn, B, Keegan, A D, Nelms, K, Garfein, E, Ihle, J N, Paul, W E, Pierce, J H, Rothman, P
Publicado em 1995

Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state.

Por Briscoe, J, Rogers, N C, Witthuhn, B A, Watling, D, Harpur, A G, Wilks, A F, Stark, G R, Ihle, J N, Kerr, I M
Publicado em 1996

A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.

Por Kohlhuber, F, Rogers, N C, Watling, D, Feng, J, Guschin, D, Briscoe, J, Witthuhn, B A, Kotenko, S V, Pestka, S, Stark, G R, Ihle, J N, Kerr, I M
Publicado em 1997