Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

Interleukin 3 (IL-3) regulates the proliferation and differentiation of hematopoietic cells. Although the IL-3 receptor chains lack kinase catalytic domains, IL-3 induces tyrosine phosphorylation of cellular proteins. To investigate the potential role of the JAK family of protein-tyrosine kinases in...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Silvennoinen, O, Witthuhn, B A, Quelle, F W, Cleveland, J L, Yi, T, Ihle, J N
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1993
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47370/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8378315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8429
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