Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

Interleukin 3 (IL-3) regulates the proliferation and differentiation of hematopoietic cells. Although the IL-3 receptor chains lack kinase catalytic domains, IL-3 induces tyrosine phosphorylation of cellular proteins. To investigate the potential role of the JAK family of protein-tyrosine kinases in...

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Hlavní autoři: Silvennoinen, O, Witthuhn, B A, Quelle, F W, Cleveland, J L, Yi, T, Ihle, J N
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC47370/
https://ncbi.nlm.nih.gov/pubmed/8378315
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