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Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.

The interleukin 6 receptor-associated signal transducer, gp130, is shared by receptor complexes for leukemia inhibitory factor, oncostatin M, ciliary neurotrophic factor, and interleukin 11. We show here that JAK2 kinase is rapidly tyrosine phosphorylated in mouse embryonic stem cells whose pluripot...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Narazaki, M, Witthuhn, B A, Yoshida, K, Silvennoinen, O, Yasukawa, K, Ihle, J N, Kishimoto, T, Taga, T
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43355/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8134389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.6.2285
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