Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.

The interleukin 6 receptor-associated signal transducer, gp130, is shared by receptor complexes for leukemia inhibitory factor, oncostatin M, ciliary neurotrophic factor, and interleukin 11. We show here that JAK2 kinase is rapidly tyrosine phosphorylated in mouse embryonic stem cells whose pluripot...

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Bibliographic Details
Main Authors: Narazaki, M, Witthuhn, B A, Yoshida, K, Silvennoinen, O, Yasukawa, K, Ihle, J N, Kishimoto, T, Taga, T
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC43355/
https://ncbi.nlm.nih.gov/pubmed/8134389
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