Internalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway.

Signalling receptors often undergo receptor-mediated endocytosis. In many cases this internalization is stimulated by ligand binding and activation of intrinsic receptor tyrosine kinases, resulting in a receptor down-regulation. We have analysed whether internalization of the interleukin 6 signal tr...

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Detalhes bibliográficos
Main Authors: Thiel, S, Behrmann, I, Dittrich, E, Muys, L, Tavernier, J, Wijdenes, J, Heinrich, P C, Graeve, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219106/
https://ncbi.nlm.nih.gov/pubmed/9461489
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