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Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

Interleukin 6 (IL-6) signal is transduced through gp130 that associates with a complex of IL-6 and IL-6 receptor. Truncations or amino acid substitutions offe introduced in the cytoplasmic region of human gp130, and the mutant cDNAs were transfected into murine interleukin 3-dependent cells to deter...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Murakami, M, Narazaki, M, Hibi, M, Yawata, H, Yasukawa, K, Hamaguchi, M, Taga, T, Kishimoto, T
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53132/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1662392/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11349
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