Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

Interleukin 6 (IL-6) signal is transduced through gp130 that associates with a complex of IL-6 and IL-6 receptor. Truncations or amino acid substitutions offe introduced in the cytoplasmic region of human gp130, and the mutant cDNAs were transfected into murine interleukin 3-dependent cells to deter...

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Autores principales: Murakami, M, Narazaki, M, Hibi, M, Yawata, H, Yasukawa, K, Hamaguchi, M, Taga, T, Kishimoto, T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC53132/
https://ncbi.nlm.nih.gov/pubmed/1662392
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