Regulation of the Jak2 Tyrosine Kinase by Its Pseudokinase Domain
Activation of Jak tyrosine kinases through hematopoietic cytokine receptors occurs as a consequence of ligand-induced aggregation of receptor-associated Jaks and their subsequent autophosphorylation. Jak kinases consist of a C-terminal tyrosine kinase domain, a pseudokinase domain of unknown functio...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85631/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10779328/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.10.3387-3395.2000 |
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