Regulation of the Jak2 Tyrosine Kinase by Its Pseudokinase Domain

Activation of Jak tyrosine kinases through hematopoietic cytokine receptors occurs as a consequence of ligand-induced aggregation of receptor-associated Jaks and their subsequent autophosphorylation. Jak kinases consist of a C-terminal tyrosine kinase domain, a pseudokinase domain of unknown functio...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Saharinen, Pipsa, Takaluoma, Kati, Silvennoinen, Olli
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2000
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85631/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10779328/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.10.3387-3395.2000
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