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Regulation of the Jak2 Tyrosine Kinase by Its Pseudokinase Domain

Activation of Jak tyrosine kinases through hematopoietic cytokine receptors occurs as a consequence of ligand-induced aggregation of receptor-associated Jaks and their subsequent autophosphorylation. Jak kinases consist of a C-terminal tyrosine kinase domain, a pseudokinase domain of unknown functio...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Saharinen, Pipsa, Takaluoma, Kati, Silvennoinen, Olli
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2000
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85631/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10779328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.10.3387-3395.2000
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