A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.

Lignende værker

• Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state.
  af: Briscoe, J, et al.
  Udgivet: (1996)
• Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes.
  af: Beadling, C, et al.
  Udgivet: (1994)
• A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.
  af: Guschin, D, et al.
  Udgivet: (1995)
• Transcription factors induced by interferons alpha and gamma.
  af: Imam, A M, et al.
  Udgivet: (1990)
• Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop.
  af: Feng, J, et al.
  Udgivet: (1997)