A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.

Cell lines that are mutated in interferon (IFN) responses have been critical in establishing an essential role for the JAK family of nonreceptor tyrosine kinases in interferon signalling. Mutant gamma1A cells have previously been shown to be complemented by overexpression of JAK2. Here, it is shown...

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Detalhes bibliográficos
Main Authors: Kohlhuber, F, Rogers, N C, Watling, D, Feng, J, Guschin, D, Briscoe, J, Witthuhn, B A, Kotenko, S V, Pestka, S, Stark, G R, Ihle, J N, Kerr, I M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231795/
https://ncbi.nlm.nih.gov/pubmed/9001223
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