Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop.

Ítems similars

• Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase.
  per: Zhu, X, et al.
  Publicat: (1997)
• A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.
  per: Kohlhuber, F, et al.
  Publicat: (1997)
• The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop.
  per: Yasukawa, H, et al.
  Publicat: (1999)
• Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes.
  per: Beadling, C, et al.
  Publicat: (1994)
• syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction
  per: El-Hillal, O., et al.
  Publicat: (1997)