Inhibition of Bcr serine kinase by tyrosine phosphorylation.

The first exon of the BCR gene encodes a new serine/threonine protein kinase. Abnormal fusion of the BCR and ABL genes, resulting from the formation of the Philadelphia chromosome (Ph), is the hallmark of Ph-positive leukemia. We have previously demonstrated that the Bcr protein is tyrosine phosphor...

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Autors principals: Liu, J, Wu, Y, Ma, G Z, Lu, D, Haataja, L, Heisterkamp, N, Groffen, J, Arlinghaus, R B
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC231082/
https://ncbi.nlm.nih.gov/pubmed/8622703
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