Inhibition of protein phosphorylation modulates expression of the Jak family protein tyrosine kinases.

Treatment of murine Friend cells with a dose of the protein kinase inhibitor staurosporine, which is able to block the response of the cells to interferons, appears to inhibit phosphorylation of Jak proteins and, interestingly, to specifically reduce tyk2 and Jak1 expression and to increase Jak2 bot...

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Bibliografische gegevens

Gepubliceerd in:	J Virol
Hoofdauteurs:	Fiorucci, G, Percario, Z A, Marcolin, C, Coccia, E M, Affabris, E, Romeo, G
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1995
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7637029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.9.5833-5837.1995
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