Inhibition of protein phosphorylation modulates expression of the Jak family protein tyrosine kinases.
Treatment of murine Friend cells with a dose of the protein kinase inhibitor staurosporine, which is able to block the response of the cells to interferons, appears to inhibit phosphorylation of Jak proteins and, interestingly, to specifically reduce tyk2 and Jak1 expression and to increase Jak2 bot...
Збережено в:
| Опубліковано в:: | J Virol |
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| Автори: | , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Microbiology (ASM)
1995
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7637029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.9.5833-5837.1995 |
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