Tumor-derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells

por Sethi, Nilay, Dai, Xudong, Winter, Christopher G., Kang, Yibin
Publicado 2011

Chest Radiographic Patterns and the Transmission of Tuberculosis: Implications for Automated Systems

por Lau, Angela, Barrie, James, Winter, Christopher, Elamy, Abdel-Halim, Tyrrell, Gregory, Long, Richard
Publicado en PLoS One (2016)

Is there a fundamental flaw in Canada’s post-arrival immigrant surveillance system for tuberculosis?

por Long, Richard, Asadi, Leyla, Heffernan, Courtney, Barrie, James, Winter, Christopher, Egedahl, Mary Lou, Paulsen, Catherine, Kunimoto, Brenden, Menzies, Dick
Publicado en PLoS One (2019)

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

por Sanda, Takaomi, Li, Xiaoyu, Gutierrez, Alejandro, Ahn, Yebin, Neuberg, Donna S., O'Neil, Jennifer, Strack, Peter R., Winter, Christopher G., Winter, Stuart S., Larson, Richard S., von Boehmer, Harald, Look, A. Thomas
Publicado 2010

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors

por O'Neil, Jennifer, Grim, Jonathan, Strack, Peter, Rao, Sudhir, Tibbitts, Deanne, Winter, Christopher, Hardwick, James, Welcker, Markus, Meijerink, Jules P., Pieters, Rob, Draetta, Giulio, Sears, Rosalie, Clurman, Bruce E., Look, A. Thomas
Publicado 2007

Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition

por Lampa, Michael, Arlt, Heike, He, Timothy, Ospina, Beatriz, Reeves, Jason, Zhang, Bailin, Murtie, Joshua, Deng, Gejing, Barberis, Claude, Hoffmann, Dietmar, Cheng, Hong, Pollard, Jack, Winter, Christopher, Richon, Victoria, Garcia-Escheverria, Carlos, Adrian, Francisco, Wiederschain, Dmitri, Srinivasan, Lakshmi
Publicado en PLoS One (2017)

Pan-TGFβ inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade

por Greco, Rita, Qu, Hongjing, Qu, Hui, Theilhaber, Joachim, Shapiro, Gary, Gregory, Richard, Winter, Christopher, Malkova, Natalia, Sun, Frank, Jaworski, Julie, Best, Annie, Pao, Lily, Hebert, Andrew, Levit, Mikhail, Protopopov, Alexei, Pollard, Jack, Bahjat, Keith, Wiederschain, Dmitri, Sharma, Sharad
Publicado en Oncoimmunology (2020)

Presenilin-Based Genetic Screens in Drosophila melanogaster Identify Novel Notch Pathway Modifiers

por Mahoney, Matt B., Parks, Annette L., Ruddy, David A., Tiong, Stanley Y. K., Esengil, Hanife, Phan, Alexander C., Philandrinos, Panos, Winter, Christopher G., Chatterjee, Runa, Huppert, Kari, Fisher, William W., L'Archeveque, Lynn, Mapa, Felipa A., Woo, Wendy, Ellis, Michael C., Curtis, Daniel
Publicado 2006

Combination of the mTOR Inhibitor Ridaforolimus and the Anti-IGF1R Monoclonal Antibody Dalotuzumab: Preclinical Characterization and Phase I Clinical Trial

por Di Cosimo, Serena, Sathyanarayanan, Sriram, Bendell, Johanna C., Cervantes, Andrés, Stein, Mark N., Braña, Irene, Roda, Desamparados, Haines, Brian B., Zhang, Theresa, Winter, Christopher G., Jha, Sharda, Xu, Youyuan, Frazier, Jason, Klinghoffer, Richard A., Leighton-Swayze, Ann, Song, Yang, Ebbinghaus, Scot, Baselga, José
Publicado en Clin Cancer Res (2014)

Oncogenic dependency on β-catenin in liver cancer cell lines correlates with pathway activation

por Ding, Zhihu, Shi, Chaomei, Jiang, Lan, Tolstykh, Tatiana, Cao, Hui, Bangari, Dinesh S., Ryan, Susan, Levit, Mikhail, Jin, Taiguang, Mamaat, Karl, Yu, Qunyan, Qu, Hui, Hopke, Joern, Cindhuchao, May, Hoffmann, Dietmar, Sun, Fangxian, Helms, Mike W., Jahn-Hofmann, Kerstin, Scheidler, Sabine, Schweizer, Liang, Fang, Douglas D., Pollard, Jack, Winter, Christopher, Wiederschain, Dmitri
Publicado en Oncotarget (2017)

Identification of the endosomal sorting complex required for transport-I (ESCRT-I) as an important modulator of anti-miR uptake by cancer cells

por Wagenaar, Timothy R., Tolstykh, Tatiana, Shi, Chaomei, Jiang, Lan, Zhang, JingXin, Li, Zhifang, Yu, Qunyan, Qu, Hui, Sun, Fangxian, Cao, Hui, Pollard, Jack, Dai, Shujia, Gao, Qiang, Zhang, Bailin, Arlt, Heike, Cindhuchao, May, Hoffmann, Dietmar, Light, Madelyn, Jensen, Karin, Hopke, Joern, Newcombe, Richard, Garcia-Echeverria, Carlos, Winter, Christopher, Zabludoff, Sonya, Wiederschain, Dmitri
Publicado en Nucleic Acids Res (2015)

Synthetic Lethality of Retinoblastoma Mutant Cells in the Drosophila Eye by Mutation of a Novel Peptidyl Prolyl Isomerase Gene

por Edgar, Kyle A., Belvin, Marcia, Parks, Annette L., Whittaker, Kellie, Mahoney, Matt B., Nicoll, Monique, Park, Christopher C., Winter, Christopher G., Chen, Feng, Lickteig, Kim, Ahmad, Ferhad, Esengil, Hanife, Lorenzi, Matthew V., Norton, Amanda, Rupnow, Brent A., Shayesteh, Laleh, Tabios, Mariano, Young, Lynn M., Carroll, Pamela M., Kopczynski, Casey, Plowman, Gregory D., Friedman, Lori S., Francis-Lang, Helen L.
Publicado 2005