MYC Degradation

by Farrell, Amy S., Sears, Rosalie C.
Published 2014

Epigenomic inactivation of RasGAPs activates Ras signaling in a subset of luminal B breast cancers

by Sears, Rosalie, Gray, Joe W.
Published in Cancer Discov (2017)

Protein Phosphatase 2A Regulatory Subunit B56α Associates with c-Myc and Negatively Regulates c-Myc Accumulation

by Arnold, Hugh K., Sears, Rosalie C.
Published 2006

A tumor suppressor role for PP2A-B56α through negative regulation of c-Myc and other key oncoproteins

by Arnold, Hugh K., Sears, Rosalie C.
Published 2008

Deconstructing Pancreatic Adenocarcinoma by Targeting the Conductor, MYC

by English, Isabel A., Sears, Rosalie C.
Published in Cancer Discov (2020)

A Conserved Pathway That Controls c-Myc Protein Stability through Opposing Phosphorylation Events Occurs in Yeast

by Escamilla-Powers, Julienne R., Sears, Rosalie C.
Published 2006

Feedback Regulation of c-Myc by Ribosomal Protein L11

by Dai, Mu-Shui, Sears, Rosalie, Lu, Hua
Published 2007

The use of protein phosphatase 2A activators in combination therapies for pancreas cancer

by Allen-Petersen, Brittany L., Sears, Rosalie C.
Published in Oncotarget (2019)

Mission Possible: Advances in MYC Therapeutic Targeting in Cancer

by Allen-Petersen, Brittany L., Sears, Rosalie C.
Published in BioDrugs (2019)

Deubiquitinating c-Myc: USP36 steps up in the nucleolus

by Sun, Xiao-Xin, Sears, Rosalie C, Dai, Mu-Shui
Published in Cell Cycle (2015)

The ubiquitin-specific protease USP36 is a conserved histone H2B deubiquitinase

by DeVine, Tiffany, Sears, Rosalie C., Dai, Mu-Shui
Published in Biochem Biophys Res Commun (2017)

Select Stabilization of a Tumor-Suppressive PP2A Heterotrimer

by Shah, Vidhi M., English, Isabel A., Sears, Rosalie C.
Published in Trends Pharmacol Sci (2020)

Inhibition of 5-Lipoxygenase Selectively Triggers Disruption of c-Myc Signaling in Prostate Cancer Cells

by Sarveswaran, Sivalokanathan, Chakraborty, Debrup, Chitale, Dhananjay, Sears, Rosalie, Ghosh, Jagadananda
Published in J Biol Chem (2015)

Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data

by Pelz, Carl R, Kulesz-Martin, Molly, Bagby, Grover, Sears, Rosalie C
Published 2008

Writing and erasing MYC ubiquitination and SUMOylation

by Chen, Yingxiao, Sun, Xiao-Xin, Sears, Rosalie C., Dai, Mu-Shui
Published in Genes Dis (2019)

Targeting the MYC Ubiquitination-Proteasome Degradation Pathway for Cancer Therapy

by Sun, Xiao-Xin, Li, Yanping, Sears, Rosalie C., Dai, Mu-Shui
Published in Front Oncol (2021)

Complex Transcriptional Regulatory Mechanisms Control Expression of the E2F3 Locus

by Adams, Monique R., Sears, Rosalie, Nuckolls, Faison, Leone, Gustavo, Nevins, Joseph R.
Published 2000

Inhibition of c-Myc activity by ribosomal protein L11

by Dai, Mu-Shui, Arnold, Hugh, Sun, Xiao-Xin, Sears, Rosalie, Lu, Hua
Published 2007

Inhibition of c-Myc activity by ribosomal protein L11

by Dai, Mu-Shui, Arnold, Hugh, Sun, Xiao-Xin, Sears, Rosalie, Lu, Hua
Published 2009

Studying c-Myc serine 62 phosphorylation in leukemia cells: concern over antibody cross-reactivity

by Tibbitts, Deanne C., Escamilla-Powers, Julienne R., Zhang, Xiaoli, Sears, Rosalie C.
Published 2012