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A tumor suppressor role for PP2A-B56α through negative regulation of c-Myc and other key oncoproteins

Loss or inhibition of the serine/threonine protein phosphatase 2A (PP2A) has revealed a critical tumor suppressor function for PP2A. However, PP2A has also been shown to have important roles in cell cycle progression and survival. Therefore, PP2A is not a typical tumor suppressor. This is most likel...

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Detalhes bibliográficos
Main Authors: Arnold, Hugh K., Sears, Rosalie C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045695/
https://ncbi.nlm.nih.gov/pubmed/18246411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-008-9128-9
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