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Inhibition of 5-Lipoxygenase Selectively Triggers Disruption of c-Myc Signaling in Prostate Cancer Cells

Myc is up-regulated in almost all cancer types and is the subject of intense investigation because of its pleiotropic effects controlling a broad spectrum of cell functions. However, despite its recognition as a stand-alone molecular target, development of suitable strategies to block its function i...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Sarveswaran, Sivalokanathan, Chakraborty, Debrup, Chitale, Dhananjay, Sears, Rosalie, Ghosh, Jagadananda
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335236/
https://ncbi.nlm.nih.gov/pubmed/25540201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.599035
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