Oncogenic dependency on β-catenin in liver cancer cell lines correlates with pathway activation

Hepatocellular carcinoma (HCC) represents a serious public health challenge with few therapeutic options available to cancer patients.Wnt/β-catenin pathway is thought to play a significant role in HCC pathogenesis. In this study, we confirmed high frequency of CTNNB1 (β-catenin) mutations in two ind...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ding, Zhihu, Shi, Chaomei, Jiang, Lan, Tolstykh, Tatiana, Cao, Hui, Bangari, Dinesh S., Ryan, Susan, Levit, Mikhail, Jin, Taiguang, Mamaat, Karl, Yu, Qunyan, Qu, Hui, Hopke, Joern, Cindhuchao, May, Hoffmann, Dietmar, Sun, Fangxian, Helms, Mike W., Jahn-Hofmann, Kerstin, Scheidler, Sabine, Schweizer, Liang, Fang, Douglas D., Pollard, Jack, Winter, Christopher, Wiederschain, Dmitri
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777711/
https://ncbi.nlm.nih.gov/pubmed/29383099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21298
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados