Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

To identify dysregulated pathways in distinct phases of NOTCH1-mediated T-cell leukemogenesis, as well as small-molecule inhibitors that could synergize with or substitute for γ-secretase inhibitors (GSIs) in T-cell acute lymphoblastic leukemia (T-ALL) therapy, we compared gene expression profiles i...

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Detalhes bibliográficos
Main Authors: Sanda, Takaomi, Li, Xiaoyu, Gutierrez, Alejandro, Ahn, Yebin, Neuberg, Donna S., O'Neil, Jennifer, Strack, Peter R., Winter, Christopher G., Winter, Stuart S., Larson, Richard S., von Boehmer, Harald, Look, A. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832805/
https://ncbi.nlm.nih.gov/pubmed/20007543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-235143
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