Inactivation of LEF1 in T-cell acute lymphoblastic leukemia

To further unravel the molecular pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL), we performed high-resolution array comparative genomic hybridization on diagnostic specimens from 47 children with T-ALL and identified monoallelic or biallelic LEF1 microdeletions in 11% (5 of 47) of these...

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Detalhes bibliográficos
Main Authors: Gutierrez, Alejandro, Sanda, Takaomi, Ma, Wenxue, Zhang, Jianhua, Grebliunaite, Ruta, Dahlberg, Suzanne, Neuberg, Donna, Protopopov, Alexei, Winter, Stuart S., Larson, Richard S., Borowitz, Michael J., Silverman, Lewis B., Chin, Lynda, Hunger, Stephen P., Jamieson, Catriona, Sallan, Stephen E., Look, A. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854430/
https://ncbi.nlm.nih.gov/pubmed/20124220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-234377
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