Absence of Biallelic TCRγ Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia

PURPOSE: To identify children with T-cell acute lymphoblastic leukemia (T-ALL) at high risk of induction chemotherapy failure by using DNA copy number analysis of leukemic cells collected at diagnosis. PATIENTS AND METHODS: Array comparative genomic hybridization (CGH) was performed on genomic DNA e...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Gutierrez, Alejandro, Dahlberg, Suzanne E., Neuberg, Donna S., Zhang, Jianhua, Grebliunaite, Ruta, Sanda, Takaomi, Protopopov, Alexei, Tosello, Valeria, Kutok, Jeffery, Larson, Richard S., Borowitz, Michael J., Loh, Mignon L., Ferrando, Adolfo A., Winter, Stuart S., Mullighan, Charles G., Silverman, Lewis B., Chin, Lynda, Hunger, Stephen P., Sallan, Stephen E., Look, A. Thomas
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Clinical Oncology 2010
Θέματα:
Original Reports
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940399/
https://ncbi.nlm.nih.gov/pubmed/20644084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.28.3390
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