Bioengineered heparin: Is there a future for this form of the successful therapeutic?

Tekijä Lord, Megan S, Whitelock, John M
Julkaistu 2014

Diverse Cell Signaling Events Modulated by Perlecan

Tekijä Whitelock, John M., Melrose, James, Iozzo, Renato V.
Julkaistu 2008

Optimization of bioengineered heparin/heparan sulfate production for therapeutic applications

Tekijä Lord, Megan S., Jung, MoonSun, Whitelock, John M.
Julkaisussa Bioengineered (2017)

Structure-Activity Relationships of Bioengineered Heparin/Heparan Sulfates Produced in Different Bioreactors

Tekijä Kim, Ha Na, Whitelock, John M., Lord, Megan S.
Julkaisussa Molecules (2017)

Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis

Tekijä Zoeller, Jason J., Whitelock, John M., Iozzo, Renato V.
Julkaistu 2009

Cell surface chondroitin sulphate proteoglycan 4 (CSPG4) binds to the basement membrane heparan sulphate proteoglycan, perlecan, and is involved in cell adhesion

Tekijä Tang, Fengying, Lord, Megan S, Stallcup, William B, Whitelock, John M
Julkaisussa J Biochem (2018)

The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies

Tekijä Farrugia, Brooke L., Lord, Megan S., Melrose, James, Whitelock, John M.
Julkaisussa J Histochem Cytochem (2018)

Can We Produce Heparin/Heparan Sulfate Biomimetics Using “Mother-Nature” as the Gold Standard?

Tekijä Farrugia, Brooke L., Lord, Megan S., Melrose, James, Whitelock, John M.
Julkaisussa Molecules (2015)

The Inter-α-Trypsin Inhibitor Family: Versatile Molecules in Biology and Pathology

Tekijä Lord, Megan S., Melrose, James, Day, Anthony J., Whitelock, John M.
Julkaisussa J Histochem Cytochem (2020)

Mast Cells Produce a Unique Chondroitin Sulfate Epitope

Tekijä Farrugia, Brooke L., Whitelock, John M., O’Grady, Robert, Caterson, Bruce, Lord, Megan S.
Julkaisussa J Histochem Cytochem (2015)

Platelet Factor 4 Binds to Vascular Proteoglycans and Controls Both Growth Factor Activities and Platelet Activation

Tekijä Lord, Megan S., Cheng, Bill, Farrugia, Brooke L., McCarthy, Simon, Whitelock, John M.
Julkaisussa J Biol Chem (2017)

Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains

Tekijä Kennett, Eleanor C., Rees, Martin D., Malle, Ernst, Hammer, Astrid, Whitelock, John M., Davies, Michael J.
Julkaistu 2010

Sulfation of the Bikunin Chondroitin Sulfate Chain Determines Heavy Chain·Hyaluronan Complex Formation

Tekijä Lord, Megan S., Day, Anthony J., Youssef, Peter, Zhuo, Lisheng, Watanabe, Hideto, Caterson, Bruce, Whitelock, John M.
Julkaistu 2013

The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

Tekijä Lord, Megan S., Chuang, Christine Y., Melrose, James, Davies, Michael J., Iozzo, Renato V., Whitelock, John M.
Julkaisussa Matrix Biol (2014)

Macrophages bind LDL using heparan sulfate and the perlecan protein core

Tekijä Ng, Chun-yi, Whitelock, John M., Williams, Helen, Kim, Ha Na, Medbury, Heather J., Lord, Megan S.
Julkaisussa J Biol Chem (2021)

Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan

Tekijä Elgundi, Zehra, Papanicolaou, Michael, Major, Gretel, Cox, Thomas R., Melrose, James, Whitelock, John M., Farrugia, Brooke L.
Julkaisussa Front Oncol (2020)

Similarity of Recombinant Human Perlecan Domain 1 by Alternative Expression Systems Bioactive Heterogenous Recombinant Human Perlecan D1

Tekijä Ellis, April L, Pan, Wensheng, Yang, Guang, Jones, Kim, Chuang, Christine, Whitelock, John M, DeCarlo, Arthur A
Julkaistu 2010

Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides

Tekijä Rees, Martin D., Bottle, Steven E., Fairfull-Smith, Kathryn E., Malle, Ernst, Whitelock, John M., Davies, Michael J.
Julkaistu 2009

A Biomimetic Approach toward Enhancing Angiogenesis: Recombinantly Expressed Domain V of Human Perlecan Is a Bioactive Molecule That Promotes Angiogenesis and Vascularization of Im...

Tekijä Lin, Xiaoting, Tang, Fengying, Jiang, Shouyuan, Khamis, Heba, Bongers, Andre, Whitelock, John M., Lord, Megan S., Rnjak‐Kovacina, Jelena
Julkaisussa Adv Sci (Weinh) (2020)

Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan

Tekijä Rees, Martin D., Whitelock, John M., Malle, Ernst, Chuang, Christine Y., Iozzo, Renato V., Nilasaroya, Anastasia, Davies, Michael J.
Julkaistu 2009