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Sulfation of the Bikunin Chondroitin Sulfate Chain Determines Heavy Chain·Hyaluronan Complex Formation

Inter-α-trypsin inhibitor (IαI) is a complex comprising two heavy chains (HCs) that are covalently bound by an ester bond to chondroitin sulfate (CS), which itself is attached to Ser-10 of bikunin. IαI is essential for the trans-esterification of HCs onto hyaluronan (HA). This process is important f...

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Detalhes bibliográficos
Main Authors: Lord, Megan S., Day, Anthony J., Youssef, Peter, Zhuo, Lisheng, Watanabe, Hideto, Caterson, Bruce, Whitelock, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743471/
https://ncbi.nlm.nih.gov/pubmed/23801333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404186
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