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Hyaluronidase-4 is produced by mast cells and can cleave serglycin chondroitin sulfate chains into lower molecular weight forms

Mast cells represent a heterogeneous cell population that is well-known for the production of heparin and the release of histamine upon activation. Serglycin is a proteoglycan that within mast cell α-granules is predominantly decorated with the glycosaminoglycans heparin or chondroitin sulfate (CS)...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Farrugia, Brooke L., Mizumoto, Shuji, Lord, Megan S., O'Grady, Robert L., Kuchel, Rhiannon P., Yamada, Shuhei, Whitelock, John M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663876/
https://ncbi.nlm.nih.gov/pubmed/31175155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008647
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