Involvement of Highly Sulfated Chondroitin Sulfate in the Metastasis of the Lewis Lung Carcinoma Cells

The altered expression of cell surface chondroitin sulfate (CS) and dermatan sulfate (DS) in cancer cells has been demonstrated to play a key role in malignant transformation and tumor metastasis. However, the functional highly sulfated structures in CS/DS chains and their involvement in the process...

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Main Authors: Li, Fuchuan, ten Dam, Gerdy B., Murugan, Sengottuvelan, Yamada, Shuhei, Hashiguchi, Taishi, Mizumoto, Shuji, Oguri, Kayoko, Okayama, Minoru, van Kuppevelt, Toin H., Sugahara, Kazuyuki
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662238/
https://ncbi.nlm.nih.gov/pubmed/18930920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806015200
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