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Mutations in Biosynthetic Enzymes for the Protein Linker Region of Chondroitin/Dermatan/Heparan Sulfate Cause Skeletal and Skin Dysplasias

Glycosaminoglycans, including chondroitin, dermatan, and heparan sulfate, have various roles in a wide range of biological events such as cell signaling, cell proliferation, tissue morphogenesis, and interactions with various growth factors. Their polysaccharides covalently attach to the serine resi...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Mizumoto, Shuji, Yamada, Shuhei, Sugahara, Kazuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637088/
https://ncbi.nlm.nih.gov/pubmed/26582078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/861752
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