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Hyaluronidase 1 and β-Hexosaminidase Have Redundant Functions in Hyaluronan and Chondroitin Sulfate Degradation

Hyaluronan (HA), a member of the glycosaminoglycan (GAG) family, is a critical component of the extracellular matrix. A model for HA degradation that invokes the activity of both hyaluronidases and exoglycosidases has been advanced. However, no in vivo studies have been done to determine the extent...

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Autores principales: Gushulak, Lara, Hemming, Richard, Martin, Dianna, Seyrantepe, Volkan, Pshezhetsky, Alexey, Triggs-Raine, Barbara
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351302/
https://ncbi.nlm.nih.gov/pubmed/22451654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.350447
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