Role of UDP-N-Acetylglucosamine (GlcNAc) and O-GlcNAcylation of Hyaluronan Synthase 2 in the Control of Chondroitin Sulfate and Hyaluronan Synthesis

Hyaluronan (HA) is a glycosaminoglycan present in most tissue microenvironments that can modulate many cell behaviors, including proliferation, migration, and adhesive proprieties. In contrast with other glycosaminoglycans, which are synthesized in the Golgi, HA is synthesized at the plasma membrane...

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Detalhes bibliográficos
Main Authors: Vigetti, Davide, Deleonibus, Sara, Moretto, Paola, Karousou, Eugenia, Viola, Manuela, Bartolini, Barbara, Hascall, Vincent C., Tammi, Markku, De Luca, Giancarlo, Passi, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471761/
https://ncbi.nlm.nih.gov/pubmed/22887999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.402347
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