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Can We Produce Heparin/Heparan Sulfate Biomimetics Using “Mother-Nature” as the Gold Standard?

Heparan sulfate (HS) and heparin are glycosaminoglycans (GAGs) that are heterogeneous in nature, not only due to differing disaccharide combinations, but also their sulfate modifications. HS is well known for its interactions with various growth factors and cytokines; and heparin for its clinical us...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Farrugia, Brooke L., Lord, Megan S., Melrose, James, Whitelock, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272578/
https://ncbi.nlm.nih.gov/pubmed/25751786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20034254
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