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Optimization of bioengineered heparin/heparan sulfate production for therapeutic applications

Heparin has been used clinically as an anti-coagulant for more than 100 y and the major source of this therapeutic is still animal tissues. Contamination issues in some batches of heparin over 10 y ago have highlighted the need to develop alternative methods of production of this essential drug.(1)...

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Bibliografiske detaljer
Udgivet i:Bioengineered
Main Authors: Lord, Megan S., Jung, MoonSun, Whitelock, John M.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639849/
https://ncbi.nlm.nih.gov/pubmed/28394734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2017.1301328
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