The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

Smooth muscle cell proliferation can be inhibited by heparan sulfate proteoglycans whereas the removal or digestion of heparan sulfate from perlecan promotes their proliferation. In this study we characterized the glycosaminoglycan side chains of perlecan isolated from either primary human coronary...

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Bibliographic Details
Published in:Matrix Biol
Main Authors: Lord, Megan S., Chuang, Christine Y., Melrose, James, Davies, Michael J., Iozzo, Renato V., Whitelock, John M.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030467/
https://ncbi.nlm.nih.gov/pubmed/24509440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2014.01.016
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