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The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling

Smooth muscle cell proliferation can be inhibited by heparan sulfate proteoglycans whereas the removal or digestion of heparan sulfate from perlecan promotes their proliferation. In this study we characterized the glycosaminoglycan side chains of perlecan isolated from either primary human coronary...

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Publicat a:Matrix Biol
Autors principals: Lord, Megan S., Chuang, Christine Y., Melrose, James, Davies, Michael J., Iozzo, Renato V., Whitelock, John M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030467/
https://ncbi.nlm.nih.gov/pubmed/24509440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2014.01.016
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